anno tool module anno.tl#
Alignment#
Align motif sequences using progressive MSA or pairwise reference alignment. |
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Multiple sequence alignment of motif arrays across samples. |
Motif Abundance#
PCA on motif abundance percentage vectors. |
Haplotype Calling#
Build a fused kNN graph from aligned motif arrays for haplotype analysis. |
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Cluster samples into haplotypes using Leiden on the fused graph. |
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Scan Leiden resolution and record cluster counts + modularity. |